Current Issue : April-June Volume : 2015 Issue Number : 2 Articles : 4 Articles
Standardization of herbal formulation is essential in order to assess the quality of drugs for therapeutic value. According to WHO nearly 80% of populations of developing countries rely on traditional medicines. Standardized herbal products of consistent quality and containing well-defined constituents are required for reliable clinical trials and to provide consistent beneficial therapeutic effects. Pharmacological properties of an herbal formulation depend on phytochemical constituents present therein. Development of authentic analytical methods which can reliably profile the phytochemical composition, including quantitative analysis of market/bioactive compounds and other major constituents, is a major challenge to scientists. Quality control and standardization of herbal extracts are very important to protect the integrity of herbal extracts for their pharmaceutical quality and safety. It also forms a part of prerequisite for the reproducibility of the effect of the active ingredient from one batch to another. The World Health Organization in 1999 has given a detail protocol for the standardization of herbal drugs comprising of a single content, but very little literature is available for the standardization of poly-herbal formulation. WHO guidelines for assessment of the safety, efficacy and quality of herbal medicines as a prerequisite for global harmonization are of utmost importance....
Solenostemon scutellarioides (coleus) is one of the flowering plant species belongs to family Lamiaceae. It is native to Malaysia and South East Asia. Plants need moist-drained soil to grow and typically grow 0.5-1 m tall, though some may grow as tall as 2 meters. Plants are bushy, woody-based evergreen perennial and mostly grown due to its decorative variegated leaves. It is also known as Coleus blumei and Plectranthus scutellarioides. Various species of Solenostemon scutellarioides includes Aurora, Religious Radish, Red Trailing Queen, Trailing Bleeding Heart, Trailing Salamander, Ruby Ruffles, Vulcan and Meandering Linda. Plants are generally grown as ornamental plants. They are heat-tolerant, but less grow in full sun in subtropical areas compared to shade. Main diseases that can affect coleus are downy mildew, necrotic spot virus, Mealy bugs, scale insects and whiteflies. Several studies showed very mild relaxing and hallucinogenic effects of Coleus blumei (solenostemon scutellarioides)....
The Artocarpus heterophyllus Lam. is a species of tree of the mulberry family Moraceae, known by other names jackfruit. Artocarpus heterophyllus Lam. is an important source of compounds like morin, dihydromorin, cynomacurin, artocarpin, isoartocarpin, cyloartocarpin, cycloheterophyllin, artocarpesin, oxydihydroartocarpesin, artocarpetin, norartocarpetin, cycloartinone, betulinic acid, artocarpanone and heterophylol which are useful in fever, boils, wounds, skin diseases, convulsions, diuretic, constipation, ophthalmic disorders and snake bite etc. The leaves are useful in fever, ulcers, boils wounds, skin diseases, antidiarrhoeal, analgesic and as immunomodulator. In this study Artocarpus heterophyllus was evaluated for morpho anatomical, physicochemical and powder characteristics. The obtained results could be used for identification and routine quality control tests for devoiding adulterants....
Emblica officinalis is the very popular medicine in Ayurveda, used since ancient time as a medicine for the treatment of various diseases. In the present study we have isolated the pharmacologically active marker constituents from amla and its identification was done by TLC and RP-HPLC methods. The amla wine was prepared by using Saccharomyces cerevisiae as a fermenter with addition of jaggery. The self generated alcohol (SGA) content as ethanol was observed to be 9.29%, also the higher alcohol like n-butanol, n-propanol, iso-butanol were also found in trace amount as a byproduct of alcoholic fermentation. Heavy metal analysis was carried out using AAS. The UV spectrophotometric method for amla wine was developed and validated as per ICH Q2B guidelines....
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